Preventing postoperative nausea and vomiting: Prevention in context

Neurokinin-1 Receptor Antagonists in Preventing Postoperative Nausea and Vomiting

Newly developed neurokinin-1 receptor (NK-1R) antagonists have been recently tried in the prevention of postoperative nausea and vomiting (PONV). This systematic review and meta-analysis was conducted to explore whether NK-1R antagonists were effective in preventing PONV.The PRISMA statement guidelines were followed. Randomized clinical trials (RCTs) that tested the preventive effects of NK-1R ...

Postoperative nausea and vomiting

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discus...

Postoperative Nausea and Vomiting

Prevention of Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy

Objective: To assess the efficacy of ondansetron and dexamethasone in the prevention of nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Material and Methods: This study was conducted at the Department of Surgery, Khyber Teaching Hospital, Peshawar from May 2010 to December 2010. A total of 67 patients, aged 18 years and above, scheduled for elective cholecystectomy were...

Prevention and treatment of postoperative nausea and vomiting

Side effects of surgical procedures are frequent at postoperative, pain, nausea and vomiting are common. Although there is a major concern with prevention of pain, vomiting at postoperative occurs in about 30% of patients.(1) Postoperative nausea and vomiting (PONV) are defined as development of episodes of nausea and emesis after a surgical act and before hospital discharge. Nausea is defined ...